IUI success rates.

We scored an average clinical pregnancy rate of 34.6% per couple in a study the Study Intrauterine Insemination in 1131 Cycles published in Acta Obstetricia et Gynecologica Scandinavica (2001; 80: 342-348). Only cryopreserved donor sperm from our headquarters in Denmark was used throughout the eight-year period.

What is the required sperm count post wash?

We often hear very different requirements from clinics regarding the required amount of sperm especially for IUI inseminations. Extensive research and results from years of successful use of our donor sperm in Scandinavia has shown that 2 million motile spermatozoa per ml. are sufficient. From the above mentioned article:

The number of motile spermatozoa used for insemination were not predictive of IUI-D outcome as long as at least 2 million motile spermatozoa were used. This is in agreement with the results published by Pittrof et al. (6).

Handling Procedures.

The straws will start to thaw after five seconds in open air, and therefore it is extremely important that they are transferred into liquid nitrogen as quickly as possible. To preserve quality it is important keep sperm in nitrogen at all time even during control of the specimen. We recommend that a sorting bucket is used even for transfer and control of straws. This will give the necessary time to control the deliveries and avoid accidental thawing.

Thawing.

If spermatozoa are to be washed in any way, the thawed specimen must be diluted slowly using stepwise addition of culture medium (ideally a HEPES-buffered medium, to avoid pH shifts that could occur). For donor semen add 5-times volume of sperm buffer slowly drop-wise to begin with, and then in increasingly larger volumes as the sample is progressively diluted, and not exceeding 1/10 of the current volume of the diluted specimen. Optimum yields will be achieved using a SpermFilter gradient medium or equal product.

If spermatozoa are is inseminated intra-cervical or into the uterine cavity with IUI-ready straws then a dilution is not necessary.

Straws vs. vials.

We deliver worldwide, using the most advanced sperm packaging system anywhere. Our CBS® High Security straws are the only system approved by the FDA for sperm storage, thanks to features like contamination-proof, tamper-proof end caps and a special internal compartment for ID tags.

We meet the standards of these regulators.

The American Society for Reproductive Medicine
New York State Department of Health (license number GA112)
California Tissue Bank Licensing System (license number CNC 80389)
Food and Drug Administration, USA (registration number 3003474029)
Maryland Department of Health (license number TB1292)
Danish Ministry of Health

About Cryos.

The Cryos donor program was established in 1990, with the first donor semen released after six months’ quarantine in May, 1991. Clinics in Denmark were first to receive donor semen from Cryos, followed by clinics in Norway, Finland, Iceland, the United Kingdom, Greece, Germany, Italy, Switzerland and Belgium.

Today, Cryos delivers sperm-related products to clinics or distributors in nearly fifty countries and donor semen to even more than that. With more than 10,000 units of semen distributed each year, resulting in about 1,000 pregnancies per year, Cryos is the largest sperm bank in the world.

Download forms.

If you want to order catalogs for your patients fill out our order form and fax it to us.
To report pregnancies please fill out our pregnancy report form.
Clinic supply agreement.